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The Structural Basis for mRNA Recognition and Cleavage by the Ribosome-Dependent Endonuclease RelE
Translational control is widely used to adjust gene expression levels. During the stringent response in bacteria, mRNA is degraded on the ribosome by the ribosome-dependent endonuclease, RelE. The molecular basis for recognition of the ribosome and mRNA by RelE and the mechanism of cleavage are unkn...
Autores principales: | Neubauer, Cajetan, Gao, Yong-Gui, Andersen, Kasper R., Dunham, Christine M., Kelley, Ann C., Hentschel, Jendrik, Gerdes, Kenn, Ramakrishnan, V., Brodersen, Ditlev E. |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Cell Press
2009
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2807027/ https://www.ncbi.nlm.nih.gov/pubmed/20005802 http://dx.doi.org/10.1016/j.cell.2009.11.015 |
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