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Crystallographic Insight into Collagen Recognition by Discoidin Domain Receptor 2

The discoidin domain receptors, DDR1 and DDR2, are widely expressed receptor tyrosine kinases that are activated by triple-helical collagen. They control important aspects of cell behavior and are dysregulated in several human diseases. The major DDR2-binding site in collagens I–III is a GVMGFO moti...

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Detalles Bibliográficos
Autores principales:	Carafoli, Federico, Bihan, Dominique, Stathopoulos, Stavros, Konitsiotis, Antonios D., Kvansakul, Marc, Farndale, Richard W., Leitinger, Birgit, Hohenester, Erhard
Formato:	Texto
Lenguaje:	English
Publicado:	Cell Press 2009
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2807035/ https://www.ncbi.nlm.nih.gov/pubmed/20004161 http://dx.doi.org/10.1016/j.str.2009.10.012

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