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Generation of bovine transgenics using somatic cell nuclear transfer
The ability to produce transgenic animals through the introduction of exogenous DNA has existed for many years. However, past methods available to generate transgenic animals, such as pronuclear microinjection or the use of embryonic stem cells, have either been inefficient or not available in all a...
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Formato: | Texto |
Lenguaje: | English |
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BioMed Central
2003
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC280725/ https://www.ncbi.nlm.nih.gov/pubmed/14613543 http://dx.doi.org/10.1186/1477-7827-1-81 |
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author | Hodges, Craig A Stice, Steven L |
author_facet | Hodges, Craig A Stice, Steven L |
author_sort | Hodges, Craig A |
collection | PubMed |
description | The ability to produce transgenic animals through the introduction of exogenous DNA has existed for many years. However, past methods available to generate transgenic animals, such as pronuclear microinjection or the use of embryonic stem cells, have either been inefficient or not available in all animals, bovine included. More recently somatic cell nuclear transfer has provided a method to create transgenic animals that overcomes many deficiencies present in other methods. This review summarizes the benefits of using somatic cell nuclear transfer to create bovine transgenics as well as the possible opportunities this method creates for the future. |
format | Text |
id | pubmed-280725 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2003 |
publisher | BioMed Central |
record_format | MEDLINE/PubMed |
spelling | pubmed-2807252003-12-02 Generation of bovine transgenics using somatic cell nuclear transfer Hodges, Craig A Stice, Steven L Reprod Biol Endocrinol Review The ability to produce transgenic animals through the introduction of exogenous DNA has existed for many years. However, past methods available to generate transgenic animals, such as pronuclear microinjection or the use of embryonic stem cells, have either been inefficient or not available in all animals, bovine included. More recently somatic cell nuclear transfer has provided a method to create transgenic animals that overcomes many deficiencies present in other methods. This review summarizes the benefits of using somatic cell nuclear transfer to create bovine transgenics as well as the possible opportunities this method creates for the future. BioMed Central 2003-11-07 /pmc/articles/PMC280725/ /pubmed/14613543 http://dx.doi.org/10.1186/1477-7827-1-81 Text en Copyright © 2003 Hodges and Stice; licensee BioMed Central Ltd. This is an Open Access article: verbatim copying and redistribution of this article are permitted in all media for any purpose, provided this notice is preserved along with the article's original URL. |
spellingShingle | Review Hodges, Craig A Stice, Steven L Generation of bovine transgenics using somatic cell nuclear transfer |
title | Generation of bovine transgenics using somatic cell nuclear transfer |
title_full | Generation of bovine transgenics using somatic cell nuclear transfer |
title_fullStr | Generation of bovine transgenics using somatic cell nuclear transfer |
title_full_unstemmed | Generation of bovine transgenics using somatic cell nuclear transfer |
title_short | Generation of bovine transgenics using somatic cell nuclear transfer |
title_sort | generation of bovine transgenics using somatic cell nuclear transfer |
topic | Review |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC280725/ https://www.ncbi.nlm.nih.gov/pubmed/14613543 http://dx.doi.org/10.1186/1477-7827-1-81 |
work_keys_str_mv | AT hodgescraiga generationofbovinetransgenicsusingsomaticcellnucleartransfer AT sticestevenl generationofbovinetransgenicsusingsomaticcellnucleartransfer |