Elevated PAI-1 is associated with poor clinical outcomes in pediatric patients with acute lung injury

PURPOSE: Deposition of fibrin in the alveolar space is a hallmark of acute lung injury (ALI). Plasminogen activator inhibitor-1 (PAI-1) is an antifibrinolytic agent that is activated during inflammation. Increased plasma and pulmonary edema fluid levels of PAI-1 are associated with increased mortali...

Descripción completa

Detalles Bibliográficos
Autores principales: Sapru, Anil, Curley, Martha A. Q., Brady, Sandra, Matthay, Michael A., Flori, Heidi
Formato: Texto
Lenguaje:English
Publicado: Springer-Verlag 2009
Materias:
Experimental
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2807603/
https://www.ncbi.nlm.nih.gov/pubmed/19855955
http://dx.doi.org/10.1007/s00134-009-1690-2

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2807603/
https://www.ncbi.nlm.nih.gov/pubmed/19855955
http://dx.doi.org/10.1007/s00134-009-1690-2

Ejemplares similares