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Combination antiretroviral drugs in PLGA nanoparticle for HIV-1

BACKGROUND: Combination antiretroviral (AR) therapy continues to be the mainstay for HIV treatment. However, antiretroviral drug nonadherence can lead to the development of resistance and treatment failure. We have designed nanoparticles (NP) that contain three AR drugs and characterized the size, s...

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Detalles Bibliográficos
Autores principales: Destache, Christopher J, Belgum, Todd, Christensen, Keith, Shibata, Annemarie, Sharma, Akhilesh, Dash, Alekha
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2807870/
https://www.ncbi.nlm.nih.gov/pubmed/20003214
http://dx.doi.org/10.1186/1471-2334-9-198