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Evidence of uneven selective pressure on different subsets of the conserved human genome; implications for the significance of intronic and intergenic DNA

BACKGROUND: Human genetic variation produces the wide range of phenotypic differences that make us individual. However, little is known about the distribution of variation in the most conserved functional regions of the human genome. We examined whether different subsets of the conserved human genom...

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Detalles Bibliográficos
Autores principales: Davidson, Scott, Starkey, Andrew, MacKenzie, Alasdair
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2807880/
https://www.ncbi.nlm.nih.gov/pubmed/20015390
http://dx.doi.org/10.1186/1471-2164-10-614