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A High Throughput Assay to Identify Small Molecule Modulators of Prostatic Acid Phosphatase

Prostatic acid phosphatase (PAP) is expressed in nociceptive neurons and functions as an ectonucleotidase. Injection of the secretory isoform of PAP has potent antinociceptive effects in mouse models of chronic pain. These data suggested that a small molecule activator of PAP may have utility as a n...

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Detalles Bibliográficos
Autores principales: Larsen, Rylan S, Zylka, Mark J, Scott, John E
Formato: Texto
Lenguaje:English
Publicado: Bentham Open 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2808025/
https://www.ncbi.nlm.nih.gov/pubmed/20161835
http://dx.doi.org/10.2174/1875397300903010042