A Rough Set-Based Model of HIV-1 Reverse Transcriptase Resistome

Reverse transcriptase (RT) is a viral enzyme crucial for HIV-1 replication. Currently, 12 drugs are targeted against the RT. The low fidelity of the RT-mediated transcription leads to the quick accumulation of drug-resistance mutations. The sequence-resistance relationship remains only partially und...

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Detalles Bibliográficos
Autores principales: Kierczak, Marcin, Ginalski, Krzysztof, Dramiński, Michał, Koronacki, Jacek, Rudnicki, Witold, Komorowski, Jan
Formato: Texto
Lenguaje:English
Publicado: Libertas Academica 2009
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2808174/
https://www.ncbi.nlm.nih.gov/pubmed/20140064

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2808174/
https://www.ncbi.nlm.nih.gov/pubmed/20140064

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