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Fast Microtubule Dynamics in Meiotic Spindles Measured by Single Molecule Imaging: Evidence That the Spindle Environment Does Not Stabilize Microtubules

Metaphase spindles are steady-state ensembles of microtubules that turn over rapidly and slide poleward in some systems. Since the discovery of dynamic instability in the mid-1980s, models for spindle morphogenesis have proposed that microtubules are stabilized by the spindle environment. We used si...

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Detalles Bibliográficos
Autores principales: Needleman, Daniel J., Groen, Aaron, Ohi, Ryoma, Maresca, Tom, Mirny, Leonid, Mitchison, Tim
Formato: Texto
Lenguaje:English
Publicado: The American Society for Cell Biology 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2808228/
https://www.ncbi.nlm.nih.gov/pubmed/19940016
http://dx.doi.org/10.1091/mbc.E09-09-0816