Phosphorylation of Serine 11 and Serine 92 as New Positive Regulators of Human Snail1 Function: Potential Involvement of Casein Kinase-2 and the cAMP-activated Kinase Protein Kinase A

Snail1 is a major factor for epithelial-mesenchymal transition (EMT), an important event in tumor metastasis and in other pathologies. Snail1 is tightly regulated at transcriptional and posttranscriptional levels. Control of Snail1 protein stability and nuclear export by GSK3β phosphorylation is imp...

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Autores principales: MacPherson, Matthew Reid, Molina, Patricia, Souchelnytskyi, Serhiy, Wernstedt, Christer, Martin-Pérez, Jorge, Portillo, Francisco, Cano, Amparo
Formato: Texto
Lenguaje:English
Publicado: The American Society for Cell Biology 2010
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2808231/
https://www.ncbi.nlm.nih.gov/pubmed/19923321
http://dx.doi.org/10.1091/mbc.E09-06-0504

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