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Induction of a Massive Endoplasmic Reticulum and Perinuclear Space Expansion by Expression of Lamin B Receptor Mutants and the Related Sterol Reductases TM7SF2 and DHCR7

Lamin B receptor (LBR) is an inner nuclear membrane protein involved in tethering the nuclear lamina and the underlying chromatin to the nuclear envelope. In addition, LBR exhibits sterol reductase activity. Mutations in the LBR gene cause two different human diseases: Pelger-Huët anomaly and Greenb...

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Detalles Bibliográficos
Autores principales:	Zwerger, Monika, Kolb, Thorsten, Richter, Karsten, Karakesisoglou, Iakowos, Herrmann, Harald
Formato:	Texto
Lenguaje:	English
Publicado:	The American Society for Cell Biology 2010
Materias:	Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2808238/ https://www.ncbi.nlm.nih.gov/pubmed/19940018 http://dx.doi.org/10.1091/mbc.E09-08-0739

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