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Aberrant Gene Promoter Methylation Associated with Sporadic Multiple Colorectal Cancer

BACKGROUND: Colorectal cancer (CRC) multiplicity has been mainly related to polyposis and non-polyposis hereditary syndromes. In sporadic CRC, aberrant gene promoter methylation has been shown to play a key role in carcinogenesis, although little is known about its involvement in multiplicity. To as...

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Detalles Bibliográficos
Autores principales: Gonzalo, Victoria, Lozano, Juan José, Muñoz, Jenifer, Balaguer, Francesc, Pellisé, Maria, de Miguel, Cristina Rodríguez, Andreu, Montserrat, Jover, Rodrigo, Llor, Xavier, Giráldez, M. Dolores, Ocaña, Teresa, Serradesanferm, Anna, Alonso-Espinaco, Virginia, Jimeno, Mireya, Cuatrecasas, Miriam, Sendino, Oriol, Castellví-Bel, Sergi, Castells, Antoni
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2808250/
https://www.ncbi.nlm.nih.gov/pubmed/20098741
http://dx.doi.org/10.1371/journal.pone.0008777