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Molecular Signatures of Quiescent, Mobilized and Leukemia-Initiating Hematopoietic Stem Cells

Hematopoietic stem cells (HSC) are rare, multipotent cells capable of generating all specialized cells of the blood system. Appropriate regulation of HSC quiescence is thought to be crucial to maintain their lifelong function; however, the molecular pathways controlling stem cell quiescence remain p...

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Detalles Bibliográficos
Autores principales: Forsberg, E. Camilla, Passegué, Emmanuelle, Prohaska, Susan S., Wagers, Amy J., Koeva, Martina, Stuart, Joshua M., Weissman, Irving L.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2808351/
https://www.ncbi.nlm.nih.gov/pubmed/20098702
http://dx.doi.org/10.1371/journal.pone.0008785

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