Analysis of Memory B Cell Responses and Isolation of Novel Monoclonal Antibodies with Neutralizing Breadth from HIV-1-Infected Individuals

BACKGROUND: The isolation of human monoclonal antibodies (mAbs) that neutralize a broad spectrum of primary HIV-1 isolates and the characterization of the human neutralizing antibody B cell response to HIV-1 infection are important goals that are central to the design of an effective antibody-based...

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Detalles Bibliográficos
Autores principales: Corti, Davide, Langedijk, Johannes P. M., Hinz, Andreas, Seaman, Michael S., Vanzetta, Fabrizia, Fernandez-Rodriguez, Blanca M., Silacci, Chiara, Pinna, Debora, Jarrossay, David, Balla-Jhagjhoorsingh, Sunita, Willems, Betty, Zekveld, Maria J., Dreja, Hanna, O'Sullivan, Eithne, Pade, Corinna, Orkin, Chloe, Jeffs, Simon A., Montefiori, David C., Davis, David, Weissenhorn, Winfried, McKnight, Áine, Heeney, Jonathan L., Sallusto, Federica, Sattentau, Quentin J., Weiss, Robin A., Lanzavecchia, Antonio
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2808385/
https://www.ncbi.nlm.nih.gov/pubmed/20098712
http://dx.doi.org/10.1371/journal.pone.0008805

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