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A Role for Non-Covalent SUMO Interaction Motifs in Pc2/CBX4 E3 Activity
BACKGROUND: Modification of proteins by the small ubiquitin like modifier (SUMO) is an essential process in mammalian cells. SUMO is covalently attached to lysines in target proteins via an enzymatic cascade which consists of E1 and E2, SUMO activating and conjugating enzymes. There is also a variab...
Autores principales: | Merrill, Jacqueline C., Melhuish, Tiffany A., Kagey, Michael H., Yang, Shen-Hsi, Sharrocks, Andrew D., Wotton, David |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2808386/ https://www.ncbi.nlm.nih.gov/pubmed/20098713 http://dx.doi.org/10.1371/journal.pone.0008794 |
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