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CXCR4 acts as a costimulator during thymic β selection

Passage through the β-selection developmental checkpoint requires productive rearrangement of Tcrb gene segments and formation of a pre-T cell receptor (pre-TCR) on the surface of CD4(–)CD8(–) thymocytes. How other receptors influence β-selection is less well understood. Here, we define a new role f...

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Detalles Bibliográficos
Autores principales:	Trampont, Paul C., Tosello-Trampont, Annie-Carole, Shen, Yuelei, Duley, Amanda K., Bender, Timothy P., Sutherland, Ann E., Littman, Dan R., Ravichandran, Kodi S.
Formato:	Texto
Lenguaje:	English
Publicado:	2009
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2808461/ https://www.ncbi.nlm.nih.gov/pubmed/20010845 http://dx.doi.org/10.1038/ni.1830

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