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The current role of renal biopsy in the management of localized renal tumors

INTRODUCTION: In the current era of nephron-sparing surgery (NSS) for localized tumors, pretreatment tissue biopsy is being revisited and re-evaluated. Whether a renal biopsy can supplement imaging investigations to change patient management is a subject of current research. MATERIALS AND METHODS: W...

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Detalles Bibliográficos
Autores principales: Gautam, Gagan, Zorn, Kevin C.
Formato: Texto
Lenguaje:English
Publicado: Medknow Publications 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2808655/
https://www.ncbi.nlm.nih.gov/pubmed/19955676
http://dx.doi.org/10.4103/0970-1591.57926
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author Gautam, Gagan
Zorn, Kevin C.
author_facet Gautam, Gagan
Zorn, Kevin C.
author_sort Gautam, Gagan
collection PubMed
description INTRODUCTION: In the current era of nephron-sparing surgery (NSS) for localized tumors, pretreatment tissue biopsy is being revisited and re-evaluated. Whether a renal biopsy can supplement imaging investigations to change patient management is a subject of current research. MATERIALS AND METHODS: We performed a database search in PubMed for manuscripts from 1988 to 2008 using the appropriate keywords. Manuscripts were selected according to their relevance to the current topic and incorporated into this review. RESULTS: Preoperative renal biopsy has been utilized to effectively distinguish between benign and malignant tumors localized to the kidney with minimal additional morbidity attributable to the procedure. Tissue diagnosis can also potentially grade renal tumors and uncover unusual malignancies. Although its acceptance remains limited, with fear of false negative results, bleeding and tumor seeding, its ability to influence management decisions has been demonstrated in literature. CONCLUSIONS: The role of preoperative renal biopsy for localized renal tumors is likely to increase rapidly in the coming times. With the expanding scope and utilization of NSS, this diagnostic modality will find increased applicability and acceptance in individualizing management protocols in the future.
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spelling pubmed-28086552010-01-25 The current role of renal biopsy in the management of localized renal tumors Gautam, Gagan Zorn, Kevin C. Indian J Urol Symposium INTRODUCTION: In the current era of nephron-sparing surgery (NSS) for localized tumors, pretreatment tissue biopsy is being revisited and re-evaluated. Whether a renal biopsy can supplement imaging investigations to change patient management is a subject of current research. MATERIALS AND METHODS: We performed a database search in PubMed for manuscripts from 1988 to 2008 using the appropriate keywords. Manuscripts were selected according to their relevance to the current topic and incorporated into this review. RESULTS: Preoperative renal biopsy has been utilized to effectively distinguish between benign and malignant tumors localized to the kidney with minimal additional morbidity attributable to the procedure. Tissue diagnosis can also potentially grade renal tumors and uncover unusual malignancies. Although its acceptance remains limited, with fear of false negative results, bleeding and tumor seeding, its ability to influence management decisions has been demonstrated in literature. CONCLUSIONS: The role of preoperative renal biopsy for localized renal tumors is likely to increase rapidly in the coming times. With the expanding scope and utilization of NSS, this diagnostic modality will find increased applicability and acceptance in individualizing management protocols in the future. Medknow Publications 2009 /pmc/articles/PMC2808655/ /pubmed/19955676 http://dx.doi.org/10.4103/0970-1591.57926 Text en © Indian Journal of Urology http://creativecommons.org/licenses/by/2.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Symposium
Gautam, Gagan
Zorn, Kevin C.
The current role of renal biopsy in the management of localized renal tumors
title The current role of renal biopsy in the management of localized renal tumors
title_full The current role of renal biopsy in the management of localized renal tumors
title_fullStr The current role of renal biopsy in the management of localized renal tumors
title_full_unstemmed The current role of renal biopsy in the management of localized renal tumors
title_short The current role of renal biopsy in the management of localized renal tumors
title_sort current role of renal biopsy in the management of localized renal tumors
topic Symposium
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2808655/
https://www.ncbi.nlm.nih.gov/pubmed/19955676
http://dx.doi.org/10.4103/0970-1591.57926
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