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Modulatory effects of α- and γ-tocopherols on 4-hydroxyestradiol induced oxidative stresses in MCF-10A breast epithelial cells

The elevated level of circulating estradiol increases the risk of breast tumor development. To gain further insight into mechanisms involved in their actions, we investigated the molecular mechanisms of 4-hydroxyestradiol (4-OHE(2)) to initiate and/or promote abnormal cell growth, and of α- or γ-toc...

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Detalles Bibliográficos
Autores principales: Lee, Eun-Ju, Oh, Seung-Yeon, Kim, Mi-Kyung, Ahn, Sei Hyun, Son, Byung Ho, Sung, Mi-Kyung
Formato: Texto
Lenguaje:English
Publicado: The Korean Nutrition Society and The Korean Society of Community Nutrition 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2808717/
https://www.ncbi.nlm.nih.gov/pubmed/20090883
http://dx.doi.org/10.4162/nrp.2009.3.3.185