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Tackling the methylome: recent methodological advances in genome-wide methylation profiling
DNA methylation of promoter CpG islands is strongly associated with gene silencing and is known as a frequent cause of loss of expression of tumor suppressor genes, as well as other genes involved in tumor formation. DNA methylation of driver genes is very likely outnumbered by the number of methyla...
| Autores principales: | , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2009
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2808741/ https://www.ncbi.nlm.nih.gov/pubmed/19930617 http://dx.doi.org/10.1186/gm106 |