Secretome: clues into pathogen infection and clinical applications

The secretome encompasses the complete set of gene products secreted by a cell. Recent studies on secretome analysis reveal that secretory proteins play an important role in pathogen infection and host-pathogen interactions. Excretory/secretory proteins of pathogens change the host cell environment...

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Detalles Bibliográficos
Autores principales: Ranganathan, Shoba, Garg, Gagan
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2009
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2808748/
https://www.ncbi.nlm.nih.gov/pubmed/19951402
http://dx.doi.org/10.1186/gm113
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author Ranganathan, Shoba
Garg, Gagan
author_facet Ranganathan, Shoba
Garg, Gagan
author_sort Ranganathan, Shoba
collection PubMed
description The secretome encompasses the complete set of gene products secreted by a cell. Recent studies on secretome analysis reveal that secretory proteins play an important role in pathogen infection and host-pathogen interactions. Excretory/secretory proteins of pathogens change the host cell environment by suppressing the immune system, to aid the proliferation of infection. Identifying secretory proteins involved in pathogen infection will lead to the discovery of potential drug targets and biomarkers for diagnostic applications.
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spelling pubmed-28087482010-11-30 Secretome: clues into pathogen infection and clinical applications Ranganathan, Shoba Garg, Gagan Genome Med Review The secretome encompasses the complete set of gene products secreted by a cell. Recent studies on secretome analysis reveal that secretory proteins play an important role in pathogen infection and host-pathogen interactions. Excretory/secretory proteins of pathogens change the host cell environment by suppressing the immune system, to aid the proliferation of infection. Identifying secretory proteins involved in pathogen infection will lead to the discovery of potential drug targets and biomarkers for diagnostic applications. BioMed Central 2009-11-30 /pmc/articles/PMC2808748/ /pubmed/19951402 http://dx.doi.org/10.1186/gm113 Text en Copyright ©2009 BioMed Central Ltd
spellingShingle Review
Ranganathan, Shoba
Garg, Gagan
Secretome: clues into pathogen infection and clinical applications
title Secretome: clues into pathogen infection and clinical applications
title_full Secretome: clues into pathogen infection and clinical applications
title_fullStr Secretome: clues into pathogen infection and clinical applications
title_full_unstemmed Secretome: clues into pathogen infection and clinical applications
title_short Secretome: clues into pathogen infection and clinical applications
title_sort secretome: clues into pathogen infection and clinical applications
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2808748/
https://www.ncbi.nlm.nih.gov/pubmed/19951402
http://dx.doi.org/10.1186/gm113
work_keys_str_mv AT ranganathanshoba secretomecluesintopathogeninfectionandclinicalapplications
AT garggagan secretomecluesintopathogeninfectionandclinicalapplications

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