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Substrate-dependent proton antiport in neurotransmitter:sodium symporters

Neurotransmitter:sodium symporters (NSS), targets for psychostimulants and therapeutic drugs, play a critical role in neurotransmission. Whereas eukaryotic NSS exhibit Cl(−)-dependent transport, bacterial NSS feature Cl(−)-independent substrate transport. Recently we showed in LeuT and Tyt1 that mut...

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Detalles Bibliográficos
Autores principales:	Zhao, Yongfang, Quick, Matthias, Shi, Lei, Mehler, Ernest L., Weinstein, Harel, Javitch, Jonathan A.
Formato:	Texto
Lenguaje:	English
Publicado:	2009
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2808765/ https://www.ncbi.nlm.nih.gov/pubmed/20081826 http://dx.doi.org/10.1038/nchembio.284

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