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GenomeRNAi: a database for cell-based RNAi phenotypes. 2009 update
The GenomeRNAi database (http://www.genomernai.org/) contains phenotypes from published cell-based RNA interference (RNAi) screens in Drosophila and Homo sapiens. The database connects observed phenotypes with annotations of targeted genes and information about the RNAi reagent used for the perturba...
Autores principales: | , , , , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2808900/ https://www.ncbi.nlm.nih.gov/pubmed/19910367 http://dx.doi.org/10.1093/nar/gkp1038 |
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author | Gilsdorf, Moritz Horn, Thomas Arziman, Zeynep Pelz, Oliver Kiner, Evgeny Boutros, Michael |
author_facet | Gilsdorf, Moritz Horn, Thomas Arziman, Zeynep Pelz, Oliver Kiner, Evgeny Boutros, Michael |
author_sort | Gilsdorf, Moritz |
collection | PubMed |
description | The GenomeRNAi database (http://www.genomernai.org/) contains phenotypes from published cell-based RNA interference (RNAi) screens in Drosophila and Homo sapiens. The database connects observed phenotypes with annotations of targeted genes and information about the RNAi reagent used for the perturbation experiment. The availability of phenotypes from Drosophila and human screens also allows for phenotype searches across species. Besides reporting quantitative data from genome-scale screens, the new release of GenomeRNAi also enables reporting of data from microscopy experiments and curated phenotypes from published screens. In addition, the database provides an updated resource of RNAi reagents and their predicted quality that are available for the Drosophila and the human genome. The new version also facilitates the integration with other genomic data sets and contains expression profiling (RNA-Seq) data for several cell lines commonly used in RNAi experiments. |
format | Text |
id | pubmed-2808900 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2010 |
publisher | Oxford University Press |
record_format | MEDLINE/PubMed |
spelling | pubmed-28089002010-01-20 GenomeRNAi: a database for cell-based RNAi phenotypes. 2009 update Gilsdorf, Moritz Horn, Thomas Arziman, Zeynep Pelz, Oliver Kiner, Evgeny Boutros, Michael Nucleic Acids Res Articles The GenomeRNAi database (http://www.genomernai.org/) contains phenotypes from published cell-based RNA interference (RNAi) screens in Drosophila and Homo sapiens. The database connects observed phenotypes with annotations of targeted genes and information about the RNAi reagent used for the perturbation experiment. The availability of phenotypes from Drosophila and human screens also allows for phenotype searches across species. Besides reporting quantitative data from genome-scale screens, the new release of GenomeRNAi also enables reporting of data from microscopy experiments and curated phenotypes from published screens. In addition, the database provides an updated resource of RNAi reagents and their predicted quality that are available for the Drosophila and the human genome. The new version also facilitates the integration with other genomic data sets and contains expression profiling (RNA-Seq) data for several cell lines commonly used in RNAi experiments. Oxford University Press 2010-01 2009-11-12 /pmc/articles/PMC2808900/ /pubmed/19910367 http://dx.doi.org/10.1093/nar/gkp1038 Text en © The Author(s) 2009. Published by Oxford University Press. http://creativecommons.org/licenses/by-nc/2.5/uk/ This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/2.5/uk/) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Articles Gilsdorf, Moritz Horn, Thomas Arziman, Zeynep Pelz, Oliver Kiner, Evgeny Boutros, Michael GenomeRNAi: a database for cell-based RNAi phenotypes. 2009 update |
title | GenomeRNAi: a database for cell-based RNAi phenotypes. 2009 update |
title_full | GenomeRNAi: a database for cell-based RNAi phenotypes. 2009 update |
title_fullStr | GenomeRNAi: a database for cell-based RNAi phenotypes. 2009 update |
title_full_unstemmed | GenomeRNAi: a database for cell-based RNAi phenotypes. 2009 update |
title_short | GenomeRNAi: a database for cell-based RNAi phenotypes. 2009 update |
title_sort | genomernai: a database for cell-based rnai phenotypes. 2009 update |
topic | Articles |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2808900/ https://www.ncbi.nlm.nih.gov/pubmed/19910367 http://dx.doi.org/10.1093/nar/gkp1038 |
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