The IntAct molecular interaction database in 2010

IntAct is an open-source, open data molecular interaction database and toolkit. Data is abstracted from the literature or from direct data depositions by expert curators following a deep annotation model providing a high level of detail. As of September 2009, IntAct contains over 200.000 curated bin...

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Autores principales: Aranda, B., Achuthan, P., Alam-Faruque, Y., Armean, I., Bridge, A., Derow, C., Feuermann, M., Ghanbarian, A. T., Kerrien, S., Khadake, J., Kerssemakers, J., Leroy, C., Menden, M., Michaut, M., Montecchi-Palazzi, L., Neuhauser, S. N., Orchard, S., Perreau, V., Roechert, B., van Eijk, K., Hermjakob, H.
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2010
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2808934/
https://www.ncbi.nlm.nih.gov/pubmed/19850723
http://dx.doi.org/10.1093/nar/gkp878
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author Aranda, B.
Achuthan, P.
Alam-Faruque, Y.
Armean, I.
Bridge, A.
Derow, C.
Feuermann, M.
Ghanbarian, A. T.
Kerrien, S.
Khadake, J.
Kerssemakers, J.
Leroy, C.
Menden, M.
Michaut, M.
Montecchi-Palazzi, L.
Neuhauser, S. N.
Orchard, S.
Perreau, V.
Roechert, B.
van Eijk, K.
Hermjakob, H.
author_facet Aranda, B.
Achuthan, P.
Alam-Faruque, Y.
Armean, I.
Bridge, A.
Derow, C.
Feuermann, M.
Ghanbarian, A. T.
Kerrien, S.
Khadake, J.
Kerssemakers, J.
Leroy, C.
Menden, M.
Michaut, M.
Montecchi-Palazzi, L.
Neuhauser, S. N.
Orchard, S.
Perreau, V.
Roechert, B.
van Eijk, K.
Hermjakob, H.
author_sort Aranda, B.
collection PubMed
description IntAct is an open-source, open data molecular interaction database and toolkit. Data is abstracted from the literature or from direct data depositions by expert curators following a deep annotation model providing a high level of detail. As of September 2009, IntAct contains over 200.000 curated binary interaction evidences. In response to the growing data volume and user requests, IntAct now provides a two-tiered view of the interaction data. The search interface allows the user to iteratively develop complex queries, exploiting the detailed annotation with hierarchical controlled vocabularies. Results are provided at any stage in a simplified, tabular view. Specialized views then allows ‘zooming in’ on the full annotation of interactions, interactors and their properties. IntAct source code and data are freely available at http://www.ebi.ac.uk/intact.
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spelling pubmed-28089342010-01-20 The IntAct molecular interaction database in 2010 Aranda, B. Achuthan, P. Alam-Faruque, Y. Armean, I. Bridge, A. Derow, C. Feuermann, M. Ghanbarian, A. T. Kerrien, S. Khadake, J. Kerssemakers, J. Leroy, C. Menden, M. Michaut, M. Montecchi-Palazzi, L. Neuhauser, S. N. Orchard, S. Perreau, V. Roechert, B. van Eijk, K. Hermjakob, H. Nucleic Acids Res Articles IntAct is an open-source, open data molecular interaction database and toolkit. Data is abstracted from the literature or from direct data depositions by expert curators following a deep annotation model providing a high level of detail. As of September 2009, IntAct contains over 200.000 curated binary interaction evidences. In response to the growing data volume and user requests, IntAct now provides a two-tiered view of the interaction data. The search interface allows the user to iteratively develop complex queries, exploiting the detailed annotation with hierarchical controlled vocabularies. Results are provided at any stage in a simplified, tabular view. Specialized views then allows ‘zooming in’ on the full annotation of interactions, interactors and their properties. IntAct source code and data are freely available at http://www.ebi.ac.uk/intact. Oxford University Press 2010-01 2009-10-22 /pmc/articles/PMC2808934/ /pubmed/19850723 http://dx.doi.org/10.1093/nar/gkp878 Text en © The Author(s) 2009. Published by Oxford University Press. http://creativecommons.org/licenses/by-nc/2.5/uk/ This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/2.5/uk/) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Articles
Aranda, B.
Achuthan, P.
Alam-Faruque, Y.
Armean, I.
Bridge, A.
Derow, C.
Feuermann, M.
Ghanbarian, A. T.
Kerrien, S.
Khadake, J.
Kerssemakers, J.
Leroy, C.
Menden, M.
Michaut, M.
Montecchi-Palazzi, L.
Neuhauser, S. N.
Orchard, S.
Perreau, V.
Roechert, B.
van Eijk, K.
Hermjakob, H.
The IntAct molecular interaction database in 2010
title The IntAct molecular interaction database in 2010
title_full The IntAct molecular interaction database in 2010
title_fullStr The IntAct molecular interaction database in 2010
title_full_unstemmed The IntAct molecular interaction database in 2010
title_short The IntAct molecular interaction database in 2010
title_sort intact molecular interaction database in 2010
topic Articles
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2808934/
https://www.ncbi.nlm.nih.gov/pubmed/19850723
http://dx.doi.org/10.1093/nar/gkp878
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