CD36 ligands promote sterile inflammation through assembly of a Toll-like receptor 4 and 6 heterodimer

In atherosclerosis and Alzheimer’s disease, deposition of the altered-self components oxidized low-density lipoprotein (LDL) and β-amyloid triggers a protracted sterile inflammatory response. Although chronic stimulation of the innate immune system is believed to underlie the pathology of these dise...

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Detalles Bibliográficos
Autores principales: Stewart, Cameron R., Stuart, Lynda M., Wilkinson, Kim, van Gils, Janine M., Deng, Jiusheng, Halle, Annett, Rayner, Katey J., Boyer, Laurent, Zhong, Ruiqin, Frazier, William A., Lacy-Hulbert, Adam, El Khoury, Joseph, Golenbock, Douglas T., Moore, Kathryn J.
Formato: Texto
Lenguaje:English
Publicado: 2009
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2809046/
https://www.ncbi.nlm.nih.gov/pubmed/20037584
http://dx.doi.org/10.1038/ni.1836

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