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The Synthesis of Truncated Polypeptides for Immune Surveillance and Viral Evasion
BACKGROUND: Cytotoxic T cells detect intracellular pathogens by surveying peptide loaded MHC class I molecules (pMHC I) on the cell surface. Effective immune surveillance also requires infected cells to present pMHC I promptly before viral progeny can escape. Rapid pMHC I presentation apparently occ...
Autores principales: | , , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2809100/ https://www.ncbi.nlm.nih.gov/pubmed/20098683 http://dx.doi.org/10.1371/journal.pone.0008692 |