LC/MS/MS Analysis of N-Terminal Protein Adducts with Improved Sensitivity: A Comparison of Selected Edman Isothiocyanate Reagents

This study provides a basis for a new and straightforward method for LC/MS/MS-based screening of N-terminal protein adducts. This procedure is denoted the “FIRE procedure” as fluorescein isothiocyanate (FITC) gave superior sensitivity by LC/MS/MS when measuring adducts (R) of electrophilic compounds...

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Detalles Bibliográficos
Autores principales: Rydberg, Per, von Stedingk, Hans, Magnér, Jörgen, Björklund, Jonas
Formato: Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2009
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2809355/
https://www.ncbi.nlm.nih.gov/pubmed/20107558
http://dx.doi.org/10.1155/2009/153472

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