Aberrant Methylation Inactivates Transforming Growth Factor β Receptor I in Head and Neck Squamous Cell Carcinoma

Background. Alterations in TGF-β signaling are common in head and neck cancer (HNSCC). Mutations in TGF-β type II receptor (T β R-II) occur frequently in HNSCC while TGF-β type I receptor (T β R-I) mutations are rare, suggesting that other molecular alterations in the TGF-β pathway are likely. To id...

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Detalles Bibliográficos
Autores principales: Muñoz-Antonia, Teresita, Torrellas-Ruiz, Mariclara, Clavell, Jonathan, Mathews, Linda A., Muro-Cacho, Carlos A., Báez, Adriana
Formato: Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2009
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2809419/
https://www.ncbi.nlm.nih.gov/pubmed/20111589
http://dx.doi.org/10.1155/2009/848695

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