Postcoital Bioavailability and Antiviral Activity of 0.5% PRO 2000 Gel: Implications for Future Microbicide Clinical Trials

BACKGROUND: The pharmacokinetics and pharmacodynamics of vaginal microbicides are typically assessed among sexually abstinent women. However, the physical act of sex may modulate gel distribution, and preclinical studies demonstrate seminal plasma interferes with the antiviral activity of several mi...

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Detalles Bibliográficos
Autores principales: Keller, Marla J., Mesquita, Pedro M. M., Torres, N. Merna, Cho, Sylvia, Shust, Gail, Madan, Rebecca P., Cohen, Hillel W., Petrie, Julie, Ford, Tara, Soto-Torres, Lydia, Profy, Albert T., Herold, Betsy C.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2809740/
https://www.ncbi.nlm.nih.gov/pubmed/20107502
http://dx.doi.org/10.1371/journal.pone.0008781

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