New Mechanism for Voltage Induced Charge Movement Revealed in GPCRs - Theory and Experiments

Depolarization induced charge movement associated currents, analogous to gating currents in channels, were recently demonstrated in G-protein coupled receptors (GPCRs), and were found to affect the receptor's Agonist binding Affinity, hence denoted AA-currents. Here we study, employing a combin...

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Detalles Bibliográficos
Autores principales: Zohar, Assaf, Dekel, Noa, Rubinsky, Boris, Parnas, Hanna
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2809744/
https://www.ncbi.nlm.nih.gov/pubmed/20107506
http://dx.doi.org/10.1371/journal.pone.0008752

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