Persistent ER Stress Induces the Spliced Leader RNA Silencing Pathway (SLS), Leading to Programmed Cell Death in Trypanosoma brucei

Trypanosomes are parasites that cycle between the insect host (procyclic form) and mammalian host (bloodstream form). These parasites lack conventional transcription regulation, including factors that induce the unfolded protein response (UPR). However, they possess a stress response mechanism, the...

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Detalles Bibliográficos
Autores principales: Goldshmidt, Hanoch, Matas, Devorah, Kabi, Anat, Carmi, Shai, Hope, Ronen, Michaeli, Shulamit
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2809764/
https://www.ncbi.nlm.nih.gov/pubmed/20107599
http://dx.doi.org/10.1371/journal.ppat.1000731

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