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Proteasome inhibitors activate autophagy as a cytoprotective response in human prostate cancer cells
The ubiquitin-proteasome and lysosome-autophagy pathways are the two major intracellular protein degradation systems that work cooperatively to maintain homeostasis. Proteasome inhibitors (PIs) have clinical activity in hematological tumors, and inhibitors of autophagy are also being evaluated as po...
| Autores principales: | , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
2009
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2809784/ https://www.ncbi.nlm.nih.gov/pubmed/19881538 http://dx.doi.org/10.1038/onc.2009.343 |