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Depletion of Liver Kupffer Cells Prevents the Development of Diet-Induced Hepatic Steatosis and Insulin Resistance

OBJECTIVE: Increased activity of the innate immune system has been implicated in the pathogenesis of the dyslipidemia and insulin resistance associated with obesity and type 2 diabetes. In this study, we addressed the potential role of Kupffer cells (liver-specific macrophages, KCs) in these metabol...

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Detalles Bibliográficos
Autores principales:	Huang, Wan, Metlakunta, Anantha, Dedousis, Nikolaos, Zhang, Pili, Sipula, Ian, Dube, John J., Scott, Donald K., O'Doherty, Robert M.
Formato:	Texto
Lenguaje:	English
Publicado:	American Diabetes Association 2010
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2809951/ https://www.ncbi.nlm.nih.gov/pubmed/19934001 http://dx.doi.org/10.2337/db09-0016

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