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Engineered Zinc Finger Protein–Mediated VEGF-A Activation Restores Deficient VEGF-A in Sensory Neurons in Experimental Diabetes
OBJECTIVE: The objectives of the study were to evaluate retrograde axonal transport of vascular endothelial growth factor A (VEGF-A) protein to sensory neurons after intramuscular administration of an engineered zinc finger protein activator of endogenous VEGF-A (VZ+434) in an experimental model of...
Autores principales: | Pawson, Elizabeth J., Duran-Jimenez, Beatriz, Surosky, Richard, Brooke, Heather E., Spratt, S. Kaye, Tomlinson, David R., Gardiner, Natalie J. |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
American Diabetes Association
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2809974/ https://www.ncbi.nlm.nih.gov/pubmed/19934008 http://dx.doi.org/10.2337/db08-1526 |
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