Determination of Artemisinin in Bulk and Pharmaceutical Dosage Forms using HPTLC

A new, simple, rapid, accurate and precise HPTLC method was developed. The detector response was linear for concentrations between 100-600 ng/spot (r =0.9931). The limits of detection and quantitation were 25 ng/spot and 75 ng/spot, respectively. The recovery study was carried out by standard additi...

Descripción completa

Detalles Bibliográficos
Autores principales: Agarwal, S. P., Ali, A., Dua, Yashomati, Ahuja, Shipra
Formato: Texto
Lenguaje:English
Publicado: Medknow Publications 2009
Materias:
Short Communication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2810065/
https://www.ncbi.nlm.nih.gov/pubmed/20177472
http://dx.doi.org/10.4103/0250-474X.51948
Descripción
Sumario:A new, simple, rapid, accurate and precise HPTLC method was developed. The detector response was linear for concentrations between 100-600 ng/spot (r =0.9931). The limits of detection and quantitation were 25 ng/spot and 75 ng/spot, respectively. The recovery study was carried out by standard addition method and was found to be 99.60±0.27. Statistical analysis proved that the method was precise, accurate and reproducible, and hence was suitable for the routine analysis of artemisinin.

Ejemplares similares