Determination of Artemisinin in Bulk and Pharmaceutical Dosage Forms using HPTLC

A new, simple, rapid, accurate and precise HPTLC method was developed. The detector response was linear for concentrations between 100-600 ng/spot (r =0.9931). The limits of detection and quantitation were 25 ng/spot and 75 ng/spot, respectively. The recovery study was carried out by standard additi...

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Detalles Bibliográficos
Autores principales: Agarwal, S. P., Ali, A., Dua, Yashomati, Ahuja, Shipra
Formato: Texto
Lenguaje:English
Publicado: Medknow Publications 2009
Materias:
Short Communication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2810065/
https://www.ncbi.nlm.nih.gov/pubmed/20177472
http://dx.doi.org/10.4103/0250-474X.51948
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author Agarwal, S. P.
Ali, A.
Dua, Yashomati
Ahuja, Shipra
author_facet Agarwal, S. P.
Ali, A.
Dua, Yashomati
Ahuja, Shipra
author_sort Agarwal, S. P.
collection PubMed
description A new, simple, rapid, accurate and precise HPTLC method was developed. The detector response was linear for concentrations between 100-600 ng/spot (r =0.9931). The limits of detection and quantitation were 25 ng/spot and 75 ng/spot, respectively. The recovery study was carried out by standard addition method and was found to be 99.60±0.27. Statistical analysis proved that the method was precise, accurate and reproducible, and hence was suitable for the routine analysis of artemisinin.
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spelling pubmed-28100652010-02-22 Determination of Artemisinin in Bulk and Pharmaceutical Dosage Forms using HPTLC Agarwal, S. P. Ali, A. Dua, Yashomati Ahuja, Shipra Indian J Pharm Sci Short Communication A new, simple, rapid, accurate and precise HPTLC method was developed. The detector response was linear for concentrations between 100-600 ng/spot (r =0.9931). The limits of detection and quantitation were 25 ng/spot and 75 ng/spot, respectively. The recovery study was carried out by standard addition method and was found to be 99.60±0.27. Statistical analysis proved that the method was precise, accurate and reproducible, and hence was suitable for the routine analysis of artemisinin. Medknow Publications 2009 /pmc/articles/PMC2810065/ /pubmed/20177472 http://dx.doi.org/10.4103/0250-474X.51948 Text en © Indian Journal of Pharmaceutical Sciences http://creativecommons.org/licenses/by/2.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Short Communication
Agarwal, S. P.
Ali, A.
Dua, Yashomati
Ahuja, Shipra
Determination of Artemisinin in Bulk and Pharmaceutical Dosage Forms using HPTLC
title Determination of Artemisinin in Bulk and Pharmaceutical Dosage Forms using HPTLC
title_full Determination of Artemisinin in Bulk and Pharmaceutical Dosage Forms using HPTLC
title_fullStr Determination of Artemisinin in Bulk and Pharmaceutical Dosage Forms using HPTLC
title_full_unstemmed Determination of Artemisinin in Bulk and Pharmaceutical Dosage Forms using HPTLC
title_short Determination of Artemisinin in Bulk and Pharmaceutical Dosage Forms using HPTLC
title_sort determination of artemisinin in bulk and pharmaceutical dosage forms using hptlc
topic Short Communication
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2810065/
https://www.ncbi.nlm.nih.gov/pubmed/20177472
http://dx.doi.org/10.4103/0250-474X.51948
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