3-O-Methylfunicone, a Selective Inhibitor of Mammalian Y-Family DNA Polymerases from an Australian Sea Salt Fungal Strain

We isolated a pol inhibitor from the cultured mycelia extract of a fungal strain isolated from natural salt from a sea salt pan in Australia, which was identified as 3-O-methylfunicone by spectroscopic analyses. This compound selectively inhibited the activities of mammalian Y-family DNA polymerases...

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Detalles Bibliográficos
Autores principales: Mizushina, Yoshiyuki, Motoshima, Hirohisa, Yamaguchi, Yasuhiro, Takeuchi, Toshifumi, Hirano, Ken, Sugawara, Fumio, Yoshida, Hiromi
Formato: Texto
Lenguaje:English
Publicado: Molecular Diversity Preservation International 2009
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2810227/
https://www.ncbi.nlm.nih.gov/pubmed/20098603
http://dx.doi.org/10.3390/md7040624

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