Isolation of C(11) Cyclopentenones from Two Didemnid Species, Lissoclinum sp. and Diplosoma sp.

A series of new C(11) cyclopentenones 1–7 was isolated, together with four known metabolites 9/10, 12 and 13, from the extract of the didemnid ascidian Lissoclinum sp. The other didemnid ascidian Diplosoma sp. contained didemnenones 1, 2 and 5, and five known metabolites 8–12. The structures of 1–7...

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Autores principales: Ogi, Takayuki, Margiastuti, Palupi, Teruya, Toshiaki, Taira, Junsei, Suenaga, Kiyotake, Ueda, Katsuhiro
Formato: Texto
Lenguaje:English
Publicado: Molecular Diversity Preservation International 2009
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2810228/
https://www.ncbi.nlm.nih.gov/pubmed/20098612
http://dx.doi.org/10.3390/md7040816
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author Ogi, Takayuki
Margiastuti, Palupi
Teruya, Toshiaki
Taira, Junsei
Suenaga, Kiyotake
Ueda, Katsuhiro
author_facet Ogi, Takayuki
Margiastuti, Palupi
Teruya, Toshiaki
Taira, Junsei
Suenaga, Kiyotake
Ueda, Katsuhiro
author_sort Ogi, Takayuki
collection PubMed
description A series of new C(11) cyclopentenones 1–7 was isolated, together with four known metabolites 9/10, 12 and 13, from the extract of the didemnid ascidian Lissoclinum sp. The other didemnid ascidian Diplosoma sp. contained didemnenones 1, 2 and 5, and five known metabolites 8–12. The structures of 1–7 were elucidated by spectroscopic analyses. Cytotoxicity of the isolated compounds was evaluated against three human cancer cell lines (HCT116, A431 and A549).
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spelling pubmed-28102282010-01-22 Isolation of C(11) Cyclopentenones from Two Didemnid Species, Lissoclinum sp. and Diplosoma sp. Ogi, Takayuki Margiastuti, Palupi Teruya, Toshiaki Taira, Junsei Suenaga, Kiyotake Ueda, Katsuhiro Mar Drugs Article A series of new C(11) cyclopentenones 1–7 was isolated, together with four known metabolites 9/10, 12 and 13, from the extract of the didemnid ascidian Lissoclinum sp. The other didemnid ascidian Diplosoma sp. contained didemnenones 1, 2 and 5, and five known metabolites 8–12. The structures of 1–7 were elucidated by spectroscopic analyses. Cytotoxicity of the isolated compounds was evaluated against three human cancer cell lines (HCT116, A431 and A549). Molecular Diversity Preservation International 2009-12-17 /pmc/articles/PMC2810228/ /pubmed/20098612 http://dx.doi.org/10.3390/md7040816 Text en © 2009 by the authors; licensee Molecular Diversity Preservation International, Basel, Switzerland http://creativecommons.org/licenses/by/3.0 This article is an open-access article distributed under the terms and conditions of the Creative Commons Attribution license (http://creativecommons.org/licenses/by/3.0/).
spellingShingle Article
Ogi, Takayuki
Margiastuti, Palupi
Teruya, Toshiaki
Taira, Junsei
Suenaga, Kiyotake
Ueda, Katsuhiro
Isolation of C(11) Cyclopentenones from Two Didemnid Species, Lissoclinum sp. and Diplosoma sp.
title Isolation of C(11) Cyclopentenones from Two Didemnid Species, Lissoclinum sp. and Diplosoma sp.
title_full Isolation of C(11) Cyclopentenones from Two Didemnid Species, Lissoclinum sp. and Diplosoma sp.
title_fullStr Isolation of C(11) Cyclopentenones from Two Didemnid Species, Lissoclinum sp. and Diplosoma sp.
title_full_unstemmed Isolation of C(11) Cyclopentenones from Two Didemnid Species, Lissoclinum sp. and Diplosoma sp.
title_short Isolation of C(11) Cyclopentenones from Two Didemnid Species, Lissoclinum sp. and Diplosoma sp.
title_sort isolation of c(11) cyclopentenones from two didemnid species, lissoclinum sp. and diplosoma sp.
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2810228/
https://www.ncbi.nlm.nih.gov/pubmed/20098612
http://dx.doi.org/10.3390/md7040816
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