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A Case of Soft Tissue Myoepithelial Tumor Arising in Masticator Space

Soft tissue myoepithelial tumors of the head and neck region are very rare, and only one case of soft tissue myoepithelial tumor occurring in the masticator space has been reported in the world literature. A case of soft tissue myoepithelial tumor with benign histomorphology, but with an invasive gr...

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Autor principal: Go, Jai Hyang
Formato: Texto
Lenguaje:English
Publicado: Yonsei University College of Medicine 2005
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2810580/
https://www.ncbi.nlm.nih.gov/pubmed/16259072
http://dx.doi.org/10.3349/ymj.2005.46.5.710
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author Go, Jai Hyang
author_facet Go, Jai Hyang
author_sort Go, Jai Hyang
collection PubMed
description Soft tissue myoepithelial tumors of the head and neck region are very rare, and only one case of soft tissue myoepithelial tumor occurring in the masticator space has been reported in the world literature. A case of soft tissue myoepithelial tumor with benign histomorphology, but with an invasive growth pattern, occurred in the masticator space of a 46-year- old male patient. Magnetic resonance imaging of paranasal sinus/nasopharynx revealed a well-defined, lobulated heterogeneous mass with high signal intensity and dense calcification in the masticator space between the left mandible ramus and pterygoid process. Grossly, the tumor was a well-circumscribed ovoid solid mass and consisted of yellowish gray glistening firm tissue. Histologically, the tumor showed a multinodular growth pattern and consisted of epithelioid cells in chondromyxoid stroma and of spindle-shaped to ovoid cells in the hyaline stroma. The tumor cells appeared bland, and no mitosis or necrosis was found within the tumor. The tumor focally invaded to adhered bone tissue. Immunohistochemically, the tumor cells were diffusely positive for epithelial membrane antigen, smooth muscle actin, but negative for other epithelial markers. Ultrastructurally, the cytoplasm of the tumor cells contained sparse microfilaments and subplasmalemmal densities. Attenuated desmosomes were commonly seen between the tumor cells.
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spelling pubmed-28105802010-01-26 A Case of Soft Tissue Myoepithelial Tumor Arising in Masticator Space Go, Jai Hyang Yonsei Med J Case Report Soft tissue myoepithelial tumors of the head and neck region are very rare, and only one case of soft tissue myoepithelial tumor occurring in the masticator space has been reported in the world literature. A case of soft tissue myoepithelial tumor with benign histomorphology, but with an invasive growth pattern, occurred in the masticator space of a 46-year- old male patient. Magnetic resonance imaging of paranasal sinus/nasopharynx revealed a well-defined, lobulated heterogeneous mass with high signal intensity and dense calcification in the masticator space between the left mandible ramus and pterygoid process. Grossly, the tumor was a well-circumscribed ovoid solid mass and consisted of yellowish gray glistening firm tissue. Histologically, the tumor showed a multinodular growth pattern and consisted of epithelioid cells in chondromyxoid stroma and of spindle-shaped to ovoid cells in the hyaline stroma. The tumor cells appeared bland, and no mitosis or necrosis was found within the tumor. The tumor focally invaded to adhered bone tissue. Immunohistochemically, the tumor cells were diffusely positive for epithelial membrane antigen, smooth muscle actin, but negative for other epithelial markers. Ultrastructurally, the cytoplasm of the tumor cells contained sparse microfilaments and subplasmalemmal densities. Attenuated desmosomes were commonly seen between the tumor cells. Yonsei University College of Medicine 2005-10-31 2005-10-31 /pmc/articles/PMC2810580/ /pubmed/16259072 http://dx.doi.org/10.3349/ymj.2005.46.5.710 Text en Copyright © 2005 The Yonsei University College of Medicine http://creativecommons.org/licenses/by-nc/3.0 This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/3.0) which permits unrestricted noncommercial use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Case Report
Go, Jai Hyang
A Case of Soft Tissue Myoepithelial Tumor Arising in Masticator Space
title A Case of Soft Tissue Myoepithelial Tumor Arising in Masticator Space
title_full A Case of Soft Tissue Myoepithelial Tumor Arising in Masticator Space
title_fullStr A Case of Soft Tissue Myoepithelial Tumor Arising in Masticator Space
title_full_unstemmed A Case of Soft Tissue Myoepithelial Tumor Arising in Masticator Space
title_short A Case of Soft Tissue Myoepithelial Tumor Arising in Masticator Space
title_sort case of soft tissue myoepithelial tumor arising in masticator space
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2810580/
https://www.ncbi.nlm.nih.gov/pubmed/16259072
http://dx.doi.org/10.3349/ymj.2005.46.5.710
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