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The Effect of Pretreatment with Thiopental on Reducing Pain Induced by Rocuronium Injection
We examined whether pretreatment with a small dose of thiopental was effective in reducing pain induced by the intravenous injection of rocuronium. Withdrawal movement was used to assess pain reduction. Ninety patients were randomly assigned to one of two groups: patients in the control group were p...
Autores principales: | , , , , , |
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Formato: | Texto |
Lenguaje: | English |
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Yonsei University College of Medicine
2005
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2810589/ https://www.ncbi.nlm.nih.gov/pubmed/16385651 http://dx.doi.org/10.3349/ymj.2005.46.6.765 |
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author | Park, Jong-Taek Choi, Jae-Chan Yoo, Young-Soo Lee, Young-Bok Kim, Soon-Yul Lim, Hyun-Kyo |
author_facet | Park, Jong-Taek Choi, Jae-Chan Yoo, Young-Soo Lee, Young-Bok Kim, Soon-Yul Lim, Hyun-Kyo |
author_sort | Park, Jong-Taek |
collection | PubMed |
description | We examined whether pretreatment with a small dose of thiopental was effective in reducing pain induced by the intravenous injection of rocuronium. Withdrawal movement was used to assess pain reduction. Ninety patients were randomly assigned to one of two groups: patients in the control group were pretreated with 2 mL saline, and those in the thiopental group were pretreated with 2 mL (50 mg) thiopental. Thiopental 5 mg/kg was injected intravenously. After a loss of consciousness, the upper arm was compressed with a rubber tourniquet, and the pretreatment drugs were administered. Thirty seconds later the tourniquet was removed and 0.6 mg/kg rocuronium was administered. Withdrawal movement was assessed using a four-grade scale: no movement, movement limited to the wrist, to the elbow or to the shoulder. The frequency of withdrawal movement in the group pretreated with thiopental was lower than in the control group (34 vs. 13, p < 0.05). We concluded that pretreatment with 2 mL (50 mg) thiopental is effective in reducing pain caused by the intravenous injection of rocuronium. |
format | Text |
id | pubmed-2810589 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2005 |
publisher | Yonsei University College of Medicine |
record_format | MEDLINE/PubMed |
spelling | pubmed-28105892010-01-26 The Effect of Pretreatment with Thiopental on Reducing Pain Induced by Rocuronium Injection Park, Jong-Taek Choi, Jae-Chan Yoo, Young-Soo Lee, Young-Bok Kim, Soon-Yul Lim, Hyun-Kyo Yonsei Med J Original Article We examined whether pretreatment with a small dose of thiopental was effective in reducing pain induced by the intravenous injection of rocuronium. Withdrawal movement was used to assess pain reduction. Ninety patients were randomly assigned to one of two groups: patients in the control group were pretreated with 2 mL saline, and those in the thiopental group were pretreated with 2 mL (50 mg) thiopental. Thiopental 5 mg/kg was injected intravenously. After a loss of consciousness, the upper arm was compressed with a rubber tourniquet, and the pretreatment drugs were administered. Thirty seconds later the tourniquet was removed and 0.6 mg/kg rocuronium was administered. Withdrawal movement was assessed using a four-grade scale: no movement, movement limited to the wrist, to the elbow or to the shoulder. The frequency of withdrawal movement in the group pretreated with thiopental was lower than in the control group (34 vs. 13, p < 0.05). We concluded that pretreatment with 2 mL (50 mg) thiopental is effective in reducing pain caused by the intravenous injection of rocuronium. Yonsei University College of Medicine 2005-12-31 2005-12-31 /pmc/articles/PMC2810589/ /pubmed/16385651 http://dx.doi.org/10.3349/ymj.2005.46.6.765 Text en Copyright © 2005 The Yonsei University College of Medicine http://creativecommons.org/licenses/by-nc/3.0 This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/3.0) which permits unrestricted noncommercial use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Original Article Park, Jong-Taek Choi, Jae-Chan Yoo, Young-Soo Lee, Young-Bok Kim, Soon-Yul Lim, Hyun-Kyo The Effect of Pretreatment with Thiopental on Reducing Pain Induced by Rocuronium Injection |
title | The Effect of Pretreatment with Thiopental on Reducing Pain Induced by Rocuronium Injection |
title_full | The Effect of Pretreatment with Thiopental on Reducing Pain Induced by Rocuronium Injection |
title_fullStr | The Effect of Pretreatment with Thiopental on Reducing Pain Induced by Rocuronium Injection |
title_full_unstemmed | The Effect of Pretreatment with Thiopental on Reducing Pain Induced by Rocuronium Injection |
title_short | The Effect of Pretreatment with Thiopental on Reducing Pain Induced by Rocuronium Injection |
title_sort | effect of pretreatment with thiopental on reducing pain induced by rocuronium injection |
topic | Original Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2810589/ https://www.ncbi.nlm.nih.gov/pubmed/16385651 http://dx.doi.org/10.3349/ymj.2005.46.6.765 |
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