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Probing the (H3-H4)(2) histone tetramer structure using pulsed EPR spectroscopy combined with site-directed spin labelling
The (H3-H4)(2) histone tetramer forms the central core of nucleosomes and, as such, plays a prominent role in assembly, disassembly and positioning of nucleosomes. Despite its fundamental role in chromatin, the tetramer has received little structural investigation. Here, through the use of pulsed el...
Autores principales: | Bowman, Andrew, Ward, Richard, El-Mkami, Hassane, Owen-Hughes, Tom, Norman, David G. |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2810997/ https://www.ncbi.nlm.nih.gov/pubmed/19914933 http://dx.doi.org/10.1093/nar/gkp1003 |
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