Sumoylation of the BLM ortholog, Sgs1, promotes telomere–telomere recombination in budding yeast

BLM and WRN are members of the RecQ family of DNA helicases, and in humans their loss is associated with syndromes characterized by genome instability and cancer predisposition. As the only RecQ DNA helicase in the yeast Saccharomyces cerevisiae, Sgs1 is known to safeguard genome integrity through i...

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Detalles Bibliográficos
Autores principales: Lu, Chia-Yin, Tsai, Cheng-Hui, Brill, Steven J., Teng, Shu-Chun
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2010
Materias:
Genome Integrity, Repair and Replication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2810998/
https://www.ncbi.nlm.nih.gov/pubmed/19906698
http://dx.doi.org/10.1093/nar/gkp1008

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2810998/
https://www.ncbi.nlm.nih.gov/pubmed/19906698
http://dx.doi.org/10.1093/nar/gkp1008

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