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Sumoylation of the BLM ortholog, Sgs1, promotes telomere–telomere recombination in budding yeast
BLM and WRN are members of the RecQ family of DNA helicases, and in humans their loss is associated with syndromes characterized by genome instability and cancer predisposition. As the only RecQ DNA helicase in the yeast Saccharomyces cerevisiae, Sgs1 is known to safeguard genome integrity through i...
| Autores principales: | , , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
Oxford University Press
2010
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2810998/ https://www.ncbi.nlm.nih.gov/pubmed/19906698 http://dx.doi.org/10.1093/nar/gkp1008 |