HIV-1 Vif binds to APOBEC3G mRNA and inhibits its translation

The HIV-1 viral infectivity factor (Vif) allows productive infection of non-permissive cells (including most natural HIV-1 targets) by counteracting the cellular cytosine deaminases APOBEC-3G (hA3G) and hA3F. The Vif-induced degradation of these restriction factors by the proteasome has been extensi...

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Detalles Bibliográficos
Autores principales: Mercenne, Gaëlle, Bernacchi, Serena, Richer, Delphine, Bec, Guillaume, Henriet, Simon, Paillart, Jean-Christophe, Marquet, Roland
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2010
Materias:
RNA
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2810999/
https://www.ncbi.nlm.nih.gov/pubmed/19910370
http://dx.doi.org/10.1093/nar/gkp1009

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2810999/
https://www.ncbi.nlm.nih.gov/pubmed/19910370
http://dx.doi.org/10.1093/nar/gkp1009

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