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HIV-1 Vif binds to APOBEC3G mRNA and inhibits its translation
The HIV-1 viral infectivity factor (Vif) allows productive infection of non-permissive cells (including most natural HIV-1 targets) by counteracting the cellular cytosine deaminases APOBEC-3G (hA3G) and hA3F. The Vif-induced degradation of these restriction factors by the proteasome has been extensi...
Autores principales: | Mercenne, Gaëlle, Bernacchi, Serena, Richer, Delphine, Bec, Guillaume, Henriet, Simon, Paillart, Jean-Christophe, Marquet, Roland |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2810999/ https://www.ncbi.nlm.nih.gov/pubmed/19910370 http://dx.doi.org/10.1093/nar/gkp1009 |
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