Cargando…

The 5′-untranslated region of the mouse mammary tumor virus mRNA exhibits cap-independent translation initiation

In this study, we demonstrate the identification of an internal ribosome entry site (IRES) within the 5′-untranslated region (5′-UTR) of the mouse mammary tumor virus (MMTV). The 5′-UTR of the full-length mRNA derived from the infectious, complete MMTV genome was cloned into a dual luciferase report...

Descripción completa

Detalles Bibliográficos
Autores principales:	Vallejos, Maricarmen, Ramdohr, Pablo, Valiente-Echeverría, Fernando, Tapia, Karla, Rodriguez, Felipe E., Lowy, Fernando, Huidobro-Toro, J. Pablo, Dangerfield, John A., López-Lastra, Marcelo
Formato:	Texto
Lenguaje:	English
Publicado:	Oxford University Press 2010
Materias:	RNA
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2811009/ https://www.ncbi.nlm.nih.gov/pubmed/19889724 http://dx.doi.org/10.1093/nar/gkp890

Ejemplares similares

Activity of the human immunodeficiency virus type 1 cell cycle-dependent internal ribosomal entry site is modulated by IRES trans-acting factors
por: Vallejos, Maricarmen, et al.
Publicado: (2011)

A cis-Acting Element Present within the gag Open Reading Frame Negatively Impacts on the Activity of the HIV-1 IRES
por: Valiente-Echeverría, Fernando, et al.
Publicado: (2013)

Functional and Structural Analysis of the Internal Ribosome Entry Site Present in the mRNA of Natural Variants of the HIV-1
por: Vallejos, Maricarmen, et al.
Publicado: (2012)

A manganese-dependent ribozyme in the 3′-untranslated region of Xenopus Vg1 mRNA
por: Kolev, Nikolay G., et al.
Publicado: (2008)

A eukaryotic-like 3′ untranslated region in Salmonella enterica hilD mRNA
por: López-Garrido, Javier, et al.
Publicado: (2014)

Non-canonical translation initiation of the spliced mRNA encoding the human T-cell leukemia virus type 1 basic leucine zipper protein
por: Cáceres, C Joaquín, et al.
Publicado: (2018)

A Rev–CBP80–eIF4AI complex drives Gag synthesis from the HIV-1 unspliced mRNA
por: Toro-Ascuy, Daniela, et al.
Publicado: (2018)

Expression of distinct RNAs from 3′ untranslated regions
por: Mercer, Tim R., et al.
Publicado: (2011)

MicroRNA-296 is enriched in cancer cells and downregulates p21(WAF1) mRNA expression via interaction with its 3′ untranslated region
por: Yoon, A-rum, et al.
Publicado: (2011)

Ribosomal scanning on the 5′-untranslated region of the human immunodeficiency virus RNA genome
por: Berkhout, Ben, et al.
Publicado: (2011)

Irregular G-quadruplexes Found in the Untranslated Regions of Human mRNAs Influence Translation
por: Bolduc, François, et al.
Publicado: (2016)

Elimination of cap structures generated by mRNA decay involves the new scavenger mRNA decapping enzyme Aph1/FHIT together with DcpS
por: Taverniti, Valerio, et al.
Publicado: (2015)

West Nile virus encodes a microRNA-like small RNA in the 3′ untranslated region which up-regulates GATA4 mRNA and facilitates virus replication in mosquito cells
por: Hussain, Mazhar, et al.
Publicado: (2012)

In-cell SHAPE uncovers dynamic interactions between the untranslated regions of the foot-and-mouth disease virus RNA
por: Diaz-Toledano, Rosa, et al.
Publicado: (2017)

HIV-2 genomic RNA accumulates in stress granules in the absence of active translation
por: Soto-Rifo, Ricardo, et al.
Publicado: (2014)

The double-stranded RNA-binding protein, Staufen1, is an IRES-transacting factor regulating HIV-1 cap-independent translation initiation
por: Ramos, Hade, et al.
Publicado: (2021)

Analysis of natural variants of the hepatitis C virus internal ribosome entry site reveals that primary sequence plays a key role in cap-independent translation
por: Barría, María Inés, et al.
Publicado: (2009)

Structural complexity of Dengue virus untranslated regions: cis-acting RNA motifs and pseudoknot interactions modulating functionality of the viral genome
por: Sztuba-Solinska, Joanna, et al.
Publicado: (2013)

Argonaute binding within 3′-untranslated regions poorly predicts gene repression
por: Chu, Yongjun, et al.
Publicado: (2020)

Binding of the 5′-untranslated region of coronavirus RNA to zinc finger CCHC-type and RNA-binding motif 1 enhances viral replication and transcription
por: Tan, Yong Wah, et al.
Publicado: (2012)

Hypermethylated-capped selenoprotein mRNAs in mammals
por: Wurth, Laurence, et al.
Publicado: (2014)

SUMO conjugation to spliceosomal proteins is required for efficient pre-mRNA splicing
por: Pozzi, Berta, et al.
Publicado: (2017)

mRNA- and factor-driven dynamic variability controls eIF4F-cap recognition for translation initiation
por: Çetin, Burak, et al.
Publicado: (2022)

The Crc global regulator binds to an unpaired A-rich motif at the Pseudomonas putida alkS mRNA coding sequence and inhibits translation initiation
por: Moreno, Renata, et al.
Publicado: (2009)

Involvement of the nuclear cap-binding protein complex in alternative splicing in Arabidopsis thaliana
por: Raczynska, Katarzyna Dorota, et al.
Publicado: (2010)

Cap-dependent translation without base-by-base scanning of an messenger ribonucleic acid
por: Paek, Ki Young, et al.
Publicado: (2012)

Identification of the Rem-responsive element of mouse mammary tumor virus
por: Müllner, Matthias, et al.
Publicado: (2008)

Nsp14 of SARS-CoV-2 inhibits mRNA processing and nuclear export by targeting the nuclear cap-binding complex
por: Katahira, Jun, et al.
Publicado: (2023)

Composition of yeast snRNPs and snoRNPs in the absence of trimethylguanosine caps reveals nuclear cap binding protein as a gained U1 component implicated in the cold-sensitivity of tgs1Δ cells
por: Schwer, Beate, et al.
Publicado: (2011)

Epitranscriptomic regulation of HIV-1 full-length RNA packaging
por: Pereira-Montecinos, Camila, et al.
Publicado: (2022)

Interactions between the HIV-1 Unspliced mRNA and Host mRNA Decay Machineries
por: Toro-Ascuy, Daniela, et al.
Publicado: (2016)

TRAP150 activates pre-mRNA splicing and promotes nuclear mRNA degradation
por: Lee, Kuo-Ming, et al.
Publicado: (2010)

A short conserved motif in ALYREF directs cap- and EJC-dependent assembly of export complexes on spliced mRNAs
por: Gromadzka, Agnieszka M., et al.
Publicado: (2016)

Extension of mRNA poly(A) tails and 3′UTRs during neuronal differentiation exhibits variable association with post-transcriptional dynamics
por: Kiltschewskij, Dylan J, et al.
Publicado: (2023)

Translation of non-capped mRNAs in a eukaryotic cell-free system: acceleration of initiation rate in the course of polysome formation
por: Alekhina, Olga M., et al.
Publicado: (2007)

The DEAD-box helicase Ded1 from yeast is an mRNP cap-associated protein that shuttles between the cytoplasm and nucleus
por: Senissar, Meriem, et al.
Publicado: (2014)

Rational design of novel N-alkyl-N capped biostable RNA nanostructures for efficient long-term inhibition of gene expression
por: Terrazas, Montserrat, et al.
Publicado: (2016)

Mouse period 2 mRNA circadian oscillation is modulated by PTB–mediated rhythmic mRNA degradation
por: Woo, Kyung-Chul, et al.
Publicado: (2009)

ArfA recognizes the lack of mRNA in the mRNA channel after RF2 binding for ribosome rescue
por: Kurita, Daisuke, et al.
Publicado: (2014)

Exploring mRNA 3′-UTR G-quadruplexes: evidence of roles in both alternative polyadenylation and mRNA shortening
por: Beaudoin, Jean-Denis, et al.
Publicado: (2013)

Cannot write session to /tmp/vufind_sessions/sess_0ukoen3ar7kad70d57fgd9bcr3