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Preferential access to genetic information from endogenous hominin ancient DNA and accurate quantitative SNP-typing via SPEX

The analysis of targeted genetic loci from ancient, forensic and clinical samples is usually built upon polymerase chain reaction (PCR)-generated sequence data. However, many studies have shown that PCR amplification from poor-quality DNA templates can create sequence artefacts at significant levels...

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Detalles Bibliográficos
Autores principales: Brotherton, Paul, Sanchez, Juan J., Cooper, Alan, Endicott, Phillip
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2811011/
https://www.ncbi.nlm.nih.gov/pubmed/19864251
http://dx.doi.org/10.1093/nar/gkp897