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Preferential access to genetic information from endogenous hominin ancient DNA and accurate quantitative SNP-typing via SPEX
The analysis of targeted genetic loci from ancient, forensic and clinical samples is usually built upon polymerase chain reaction (PCR)-generated sequence data. However, many studies have shown that PCR amplification from poor-quality DNA templates can create sequence artefacts at significant levels...
Autores principales: | , , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2811011/ https://www.ncbi.nlm.nih.gov/pubmed/19864251 http://dx.doi.org/10.1093/nar/gkp897 |