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Itk Derived Signals Regulate the Expression of Th-POK and Controls the Development of CD4(+) T Cells
T cell development is critically dependent on both the environment and signals delivered by the T cell Receptor (TCR). The Tec family kinase Itk has been suggested to be an amplifier of signals emanating from the TCR and the loss of Itk partially affects most stages of thymopoiesis. Loss of Itk also...
| Autores principales: | , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2010
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2811181/ https://www.ncbi.nlm.nih.gov/pubmed/20126642 http://dx.doi.org/10.1371/journal.pone.0008891 |