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Distinct Activities of Exonuclease 1 and Flap Endonuclease 1 at Telomeric G4 DNA

BACKGROUND: Exonuclease 1 (EXO1) and Flap endonuclease 1 (FEN1) are members of the RAD2 family of structure-specific nucleases. Genetic analysis has identified roles for EXO1 and FEN1 in replication, recombination, DNA repair and maintenance of telomeres. Telomeres are composed of G-rich repeats tha...

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Detalles Bibliográficos
Autores principales:	Vallur, Aarthy C., Maizels, Nancy
Formato:	Texto
Lenguaje:	English
Publicado:	Public Library of Science 2010
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2811187/ https://www.ncbi.nlm.nih.gov/pubmed/20126648 http://dx.doi.org/10.1371/journal.pone.0008908

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