The Behaviour of 5-Hydroxymethylcytosine in Bisulfite Sequencing

BACKGROUND: We recently showed that enzymes of the TET family convert 5-mC to 5-hydroxymethylcytosine (5-hmC) in DNA. 5-hmC is present at high levels in embryonic stem cells and Purkinje neurons. The methylation status of cytosines is typically assessed by reaction with sodium bisulfite followed by...

Descripción completa

Detalles Bibliográficos
Autores principales: Huang, Yun, Pastor, William A., Shen, Yinghua, Tahiliani, Mamta, Liu, David R., Rao, Anjana
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2811190/
https://www.ncbi.nlm.nih.gov/pubmed/20126651
http://dx.doi.org/10.1371/journal.pone.0008888

Ejemplares similares

Ejemplares similares