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A Korean Family of Familial Medullary Thyroid Cancer with Cys618Ser RET Germline Mutation
Familial medullary thyroid carcinoma (FMTC) is caused by autosomal dominant gain-of-function mutations in the RET proto-oncogene. An identifiable RET mutation can be detected in about 85% of FMTC families. The majority of germline mutations in FMTC have been found in exons 10 and 11 of the RET proto...
| Autores principales: | , , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
The Korean Academy of Medical Sciences
2010
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2811288/ https://www.ncbi.nlm.nih.gov/pubmed/20119574 http://dx.doi.org/10.3346/jkms.2010.25.2.226 |